The evidence
behind TRU NIAGEN®

How this one exceptional vitamin got the attention of the scientific community.

Nicotinamide riboside (nr) studies have more than doubled since 2014

Over 150 scientific articles have been published on our key ingredient, nicotinamide riboside, and its benefits since its discovery as an NAD booster in 2004. The number of nicotinamide riboside studies coming out each year is steadily increasing as scientists continue to uncover the potential of this remarkable nutrient. (i)

Chart showing number of articles and studies conducted on NR between 2004 and 2018 Chart showing number of articles and studies conducted on NR between 2004 and 2018

Nicotinamide riboside (NR) articles on PubMed

Our Chief Scientific Advisor led the discovery

charles brenner

Charles Brenner, Ph.D.

Our Chief Scientific Advisor led the discovery

In 2004, Dr. Charles Brenner discovered nicotinamide riboside (NR) could increase levels of a vital cellular resource. This resource is a central regulator in energy metabolism and is believed to play an important role in healthy human aging. Although NR is a naturally-occurring vitamin in milk, it’s only found in trace amounts. Based on Dr. Brenner’s patents and the established techniques of our parent company ChromaDex, NR was exclusively licensed and developed as NIAGEN®.

NIAGEN® increases NAD*, a vital resource for cellular energy

NAD (or nicotinamide adenine dinucleotide) is a vital resource found in all living cells. We use it every day. After over 100 years of studying this molecule, researchers are publishing more articles about NAD than ever before. Now we know NAD isn’t a constant resource. Things like overeating, or drinking alcohol can stress our system and cause NAD to decline. Some scientists even think this NAD decline plays a major role in how we age.

Chart showing how NAD declines with age
Chart displaying how TruNiagen increases NAD by 40-50% after 8 weeks

NIAGEN® has a remarkable ability to boost NAD in tissues that need it.*

—Charles Brenner, Ph.D.


NIAGEN® by the numbers


3 FDA Safety Notifications


5+ Published Human Clinical Studies


20+ Owned and Licensed Patents


160+ Research Collaborations

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